Antineutrophil Cytoplasmic Antibodies

Autoantibodies directed against cytoplasmic constituents of POLYMORPHONUCLEAR LEUKOCYTES and/or MONOCYTES. They are used as specific markers for GRANULOMATOSIS WITH POLYANGIITIS and other diseases, though their pathophysiological role is not clear. ANCA are routinely detected by indirect immunofluorescence with three different patterns: c-ANCA (cytoplasmic), p-ANCA (perinuclear), and atypical ANCA.

Also Known As:

ANCA; Anti-Neutrophil Cytoplasmic Antibody; Antineutrophil Cytoplasmic Antibody; Antibodies, Antineutrophil Cytoplasmic; Anti-Neutrophil Cytoplasmic Antibodies; Anti Neutrophil Cytoplasmic Antibodies; Anti Neutrophil Cytoplasmic Antibody; Anti Neutrophil Cytoplasmic Autoantibodies; Anti Neutrophil Cytoplasmic Autoantibody; Antibody, Anti-Neutrophil Cytoplasmic; Antibody, Antineutrophil Cytoplasmic; Autoantibody, Anti-Neutrophil Cytoplasmic; Autoantibody, Neutrophil Cytoplasmic; Cytoplasmic Antibody, Anti-Neutrophil; Cytoplasmic Antibody, Antineutrophil; Cytoplasmic Autoantibody, Anti-Neutrophil; Cytoplasmic Autoantibody, Neutrophil; c ANCA; p ANCA; Anti-Neutrophil Cytoplasmic Autoantibodies; Anti-Neutrophil Cytoplasmic Autoantibody; Neutrophil Cytoplasmic Autoantibodies; Neutrophil Cytoplasmic Autoantibody; c-ANCA; p-ANCA

Pharmalogical Action Categories:

Immunologic Factors

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Blood Proteins: 12459
    - Serum Globulins: 553
      - Immunoglobulins: 30480
        Antibodies: 133716
        Autoantibodies: 35785
        Antineutrophil Cytoplasmic Antibodies: 7733
    - Immunoproteins: 43
      - Immunoglobulins: 30480
        Antibodies: 133716
        Autoantibodies: 35785
        Antineutrophil Cytoplasmic Antibodies: 7733
  - Globulins: 3062
    - Serum Globulins: 553
      - Immunoglobulins: 30480
        Antibodies: 133716
        Autoantibodies: 35785
        Antineutrophil Cytoplasmic Antibodies: 7733
Biological Factors: 2472
- Biomarkers: 240291
  - Antineutrophil Cytoplasmic Antibodies: 7733

A R Clayton Selected Research

A R Clayton Research Topics

Disease

Drug/Important Bio-Agent (IBA)